Mus musculusGenAge entry for Efemp1 (Mus musculus)

Gene information (ID: 209)

Symbol
Efemp1
Name
Epidermal growth factor-containing fibulin-like extracellular matrix protein 1
Organism
Mus musculus (AnAge)
Known functions and activities
Extracellular matrix (ECM) protein of unknown function

Potential relevance to longevity and/or ageing

Observations
Knockout mice exhibited an early onset of ageing-associated phenotypes including a 20% shorted median lifespan and 30% shorter maximum lifespan, decreased body mass, lordokyphosis, reduced hair growth, and atrophy.
% change in max lifespan
Maximum lifespan is 30% lower.
% change in avg or median lifespan
Median lifespan is 20% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Knockout
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as EFEMP1
    GenAge microarray genes
    • A homolog of this gene for Homo sapiens is present as EFEMP1

    Homologs in other organisms

    Homo sapiens
    EFEMP1
    Rattus norvegicus
    Efemp1

    External links

    Mouse Genome Informatics
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (216616)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
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