Mus musculusGenAge entry for Mstn (Mus musculus)

Gene information (ID: 2080)

Symbol
Mstn
Name
myostatin
Organism
Mus musculus (AnAge)

Potential relevance to longevity and/or ageing

Observations
Mstn+/- and Mstn-/- mice were protected from age-related decline in muscle mass and contractility. MSTN+/- mice demonstrated a 15% increase in maximal lifespan when compared to Mstn+/+ and Mstn-/- mice.
% change in max lifespan
Maximum lifespan is 15% higher
% change in avg or median lifespan
15%
Lifespan Effect
Increase
Genetic Manipulation
Deletion
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Caenorhabditis elegans is present as daf-7
    • A homolog of this gene for Drosophila melanogaster is present as myo
    LongevityMap
    • A homolog of this gene for Homo sapiens is present as MSTN

    Homologs in other organisms

    Caenorhabditis elegans
    daf-7
    Danio rerio
    mstnb
    Drosophila melanogaster
    myo
    Homo sapiens
    MSTN
    Rattus norvegicus
    Mstn

    External links

    Mouse Genome Informatics
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (17700)
    Homologues
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    UniProt
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    Internet
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