Caenorhabditis elegansGenAge entry for nsun-5 (Caenorhabditis elegans)

Gene information (ID: 2079)

Symbol
nsun-5
Name
Nop2 (NOP2)/SUN domain family member
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
RNA interference of nsun-5 in worms under special diet (calorically restricted in adulthood) extends mean lifespan of worms by 17%. Similarly, RNA interference of nsun-5 in the eat-2 worm strain results in a longer lifespan.
% change in avg or median lifespan
Mean lifespan is 17% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Drosophila melanogaster is present as CG42358
    • A homolog of this gene for Saccharomyces cerevisiae is present as RCM1

    Homologs in other organisms

    Danio rerio
    nsun5
    Drosophila melanogaster
    CG42358
    Homo sapiens
    NSUN5P2
    Mus musculus
    Nsun5
    Rattus norvegicus
    Nsun5
    Saccharomyces cerevisiae
    YNL022C
    Schizosaccharomyces pombe
    SPAC2C4.06c

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (175153)
    Homologues
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    UniProt
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    Internet
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