Caenorhabditis elegansGenAge entry for mek-2 (Caenorhabditis elegans)

Gene information (ID: 2023)

Symbol
mek-2
Name
Dual specificity mitogen-activated protein kinase kinase mek-2
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
RNA interference of mek-2 results in a decrease in lifespan.
% change in avg or median lifespan
Mean lifespan is 10% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    LongevityMap
    • A homolog of this gene for Homo sapiens is present as MAP2K1
    CellAge
    • A homolog of this gene for Homo sapiens is present as MAP2K1

    Homologs in other organisms

    Danio rerio
    map2k2b
    Drosophila melanogaster
    Dsor1
    Homo sapiens
    MAP2K1
    Mus musculus
    Map2k2
    Rattus norvegicus
    Map2k2
    Saccharomyces cerevisiae
    STE7
    Schizosaccharomyces pombe
    byr1

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (171872)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
    Search Google or Search Google Scholar