Caenorhabditis elegansGenAge entry for rict-1 (Caenorhabditis elegans)

Gene information (ID: 1981)

Symbol
rict-1
Name
hypothetical protein
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
At 25 degrees celsius, rict-1 mutants fed HT115 lived slightly longer than WT, but on OP50, their lifespan was reduced. The increase in lifespan was dependent on skn-1. In contrast, at 20 C, rict-1 mutation dramatically shortened lifespan compared with WT on either food source, showing that this lifespan extension is also temperature-dependent.
% change in avg or median lifespan
Mean lifespan was approximately 10% higher.
Lifespan Effect
Increase
Genetic Manipulation
Mutation
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Mus musculus is present as Rictor
    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as RICTOR
    LongevityMap
    • A homolog of this gene for Homo sapiens is present as RICTOR

    Homologs in other organisms

    Danio rerio
    rictora
    Drosophila melanogaster
    rictor
    Homo sapiens
    RICTOR
    Mus musculus
    Rictor
    Rattus norvegicus
    Rictor

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (3565035)
    Homologues
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    UniProt
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    Internet
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