Mus musculusGenAge entry for Trpv1 (Mus musculus)

Gene information (ID: 1926)

Symbol
Trpv1
Name
transient receptor potential cation channel, subfamily V, member 1
Organism
Mus musculus (AnAge)

Potential relevance to longevity and/or ageing

Observations
Mice lacking TRPV1 pain receptors are long-lived and display a young metabolic profile at old age. Both median and maximum lifespan are extended. Longevity is extended in both genders, with 11.9% increase in male mutants and 15.9% in females.
% change in avg or median lifespan
Male median lifespan is 11.9% higher; female median lifespan is 15.9% higher.
Lifespan Effect
Increase
Genetic Manipulation
Mutation
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as TRPV1

    Homologs in other organisms

    Homo sapiens
    TRPV1
    Rattus norvegicus
    Trpv1

    External links

    Mouse Genome Informatics
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (193034)
    Homologues
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    UniProt
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    Internet
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