Drosophila melanogasterGenAge entry for GlyS (Drosophila melanogaster)

Gene information (ID: 1919)

Symbol
GlyS
Name
Glycogen synthase
Organism
Drosophila melanogaster (AnAge)

Potential relevance to longevity and/or ageing

Observations
Neuron-specific RNA interference of glycogen synthase (GlyS) in adult fly males results in a significantly longer median (10%) and maximum lifespan compared to wild-type controls. No significant lifespan increase is observed in fly females.
% change in avg or median lifespan
Male median lifespan is 10% higher.
Lifespan Effect
Increase
Genetic Manipulation
Post developmental RNA interference
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Saccharomyces cerevisiae is present as GSY2
    GenDR gene expression
    • A homolog of this gene for Mus musculus is present as Gys2

    Homologs in other organisms

    Caenorhabditis elegans
    gsy-1
    Danio rerio
    gys1
    Homo sapiens
    GYS2
    Mus musculus
    Gys2
    Rattus norvegicus
    Gys2
    Saccharomyces cerevisiae
    GSY2

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (41823)
    Homologues
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    UniProt
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    Internet
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