Drosophila melanogasterGenAge entry for Ilk (Drosophila melanogaster)

Gene information (ID: 1910)

Symbol
Ilk
Name
Integrin linked kinase
Organism
Drosophila melanogaster (AnAge)

Potential relevance to longevity and/or ageing

Observations
Both female and male heterozygous ILK (ortholog of worm PAT-4) mutants show extended lifespan.
% change in avg or median lifespan
Female median lifespan is 37-60% higher. Male median lifespan is 56-63% higher.
Lifespan Effect
Increase
Genetic Manipulation
Mutation
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Caenorhabditis elegans is present as pat-4

    Homologs in other organisms

    Caenorhabditis elegans
    pat-4
    Danio rerio
    ilk
    Homo sapiens
    ILK
    Mus musculus
    Ilk
    Rattus norvegicus
    Ilk

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (53573)
    Homologues
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    UniProt
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    Internet
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