Drosophila melanogasterGenAge entry for daw (Drosophila melanogaster)

Gene information (ID: 1899)

Symbol
daw
Name
dawdle
Organism
Drosophila melanogaster (AnAge)

Potential relevance to longevity and/or ageing

Observations
Post developmental RNA interference of Daw in the whole body increases lifespan by up to 35%. Tissue specific RNA interference also increases lifespan mildly (by ~11%) in muscle but not in adipose tissue (where it decreases lifespan).
% change in avg or median lifespan
Mean lifespan is 35.3% higher.
Lifespan Effect
Increase
Genetic Manipulation
Post developmental RNA interference
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Caenorhabditis elegans is present as daf-7

    Homologs in other organisms

    Caenorhabditis elegans
    daf-7
    Rattus norvegicus
    Inhbc

    External links

    FlyBase
    Search
    Ensembl
    Search
    Entrez Gene
    View on Entrez Gene database (33474)
    Homologues
    Search HomoloGene
    UniProt
    Search
    Internet
    Search Google or Search Google Scholar