Mus musculusGenAge entry for Myc (Mus musculus)

Gene information (ID: 1876)

Symbol
Myc
Name
myelocytomatosis oncogene
Organism
Mus musculus (AnAge)

Potential relevance to longevity and/or ageing

Observations
Haploinsufficient Myc mice are more active, have a higher metabolic rate and healthier lipid metabolism, and display resistance to several age-associated pathologies, including osteoporosis, cardiac fibrosis, and immunosenescence. Additionally, both male and female mutants live longer than the wild type.
% change in avg or median lifespan
Male median lifespan is ~10% higher; Female median lifespan is ~21%.
Lifespan Effect
Increase
Genetic Manipulation
Mutation
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as MYC
    CellAge
    • A homolog of this gene for Homo sapiens is present as MYC

    Homologs in other organisms

    Danio rerio
    mycb
    Homo sapiens
    MYC
    Rattus norvegicus
    Myc

    External links

    Mouse Genome Informatics
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (17869)
    Homologues
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    UniProt
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    Internet
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