Saccharomyces cerevisiaeGenAge entry for OST3 (Saccharomyces cerevisiae)

Gene information (ID: 1868)

Symbol
OST3
Name
dolichyl-diphosphooligosaccharide--protein glycotransferase OST3
Organism
Saccharomyces cerevisiae (AnAge)

Potential relevance to longevity and/or ageing

Observations
Deletion of ost3, a target of the unfolded protein response signaling, increases replicative lifespan.
% change in avg or median lifespan
Mean lifespan is 20% higher.
Lifespan Effect
Increase
Genetic Manipulation
Deletion
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    LongevityMap
    • A homolog of this gene for Homo sapiens is present as TUSC3

    Homologs in other organisms

    Caenorhabditis elegans
    ZK686.3
    Danio rerio
    magt1
    Drosophila melanogaster
    Ostgamma
    Homo sapiens
    TUSC3
    Mus musculus
    Tusc3
    Rattus norvegicus
    Tusc3
    Schizosaccharomyces pombe
    ost3

    External links

    Saccharomyces Genome Database
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (854252)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
    Search Google or Search Google Scholar