Saccharomyces cerevisiaeGenAge entry for VPS20 (Saccharomyces cerevisiae)

Gene information (ID: 1745)

Symbol
VPS20
Aliases
CHM6; VPL10; VPT20
Name
Vacuolar Protein Sorting 20
Organism
Saccharomyces cerevisiae (AnAge)

Potential relevance to longevity and/or ageing

Observations
VPS20 deletion decreases mean and maximum replicative lifespan under ad libitum, and cancels the dietary restriction-induced replicative lifespan extension.
% change in max lifespan
Maximum lifespan is 19% lower.
% change in avg or median lifespan
Average lifespan is 16% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Deletion
Longevity Category
Necessary for fitness
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Caenorhabditis elegans is present as vps-20
    GenDR gene manipulations
    • This gene is present as VPS20

    Homologs in other organisms

    Caenorhabditis elegans
    vps-20
    Danio rerio
    chmp6
    Drosophila melanogaster
    Vps20
    Homo sapiens
    CHMP6
    Mus musculus
    Chmp6
    Rattus norvegicus
    Chmp6
    Schizosaccharomyces pombe
    vps20

    External links

    Saccharomyces Genome Database
    Search
    Ensembl
    Search
    Entrez Gene
    View on Entrez Gene database (855101)
    Homologues
    Search HomoloGene
    UniProt
    Search
    Internet
    Search Google or Search Google Scholar