Saccharomyces cerevisiaeGenAge entry for GCN2 (Saccharomyces cerevisiae)

Gene information (ID: 1685)

Symbol
GCN2
Aliases
AAS1; AAS102; NDR2
Name
General Control Nonderepressible
Organism
Saccharomyces cerevisiae (AnAge)

Potential relevance to longevity and/or ageing

Observations
Replicative lifespan decreased by 10% in a strain
% change in avg or median lifespan
Replicative lifespan is 10% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Deletion
Longevity Category
Necessary for fitness
Primary reference
    Observations
    Replicative lifespan decreased by by 10-20% in both alpha and a strains
    % change in avg or median lifespan
    Replicative lifespan is 10-20% higher.
    Lifespan Effect
    Increase
    Genetic Manipulation
    Deletion
    Longevity Category
    Anti-Longevity
    Primary reference

      In other databases

      GenDR gene manipulations
      • A homolog of this gene for Caenorhabditis elegans is present as gcn-2

      Homologs in other organisms

      Caenorhabditis elegans
      gcn-2
      Drosophila melanogaster
      Gcn2
      Homo sapiens
      EIF2AK4
      Mus musculus
      Eif2ak4
      Rattus norvegicus
      Eif2ak4
      Schizosaccharomyces pombe
      gcn2

      External links

      Saccharomyces Genome Database
      Search
      Ensembl
      Search
      Entrez Gene
      View on Entrez Gene database (851877)
      Homologues
      Search HomoloGene
      UniProt
      Search
      Internet
      Search Google or Search Google Scholar