Mus musculusGenAge entry for Cdkn1a (Mus musculus)

Gene information (ID: 109)

Symbol
Cdkn1a
Aliases
P21; CDKI; CIP1; SDI1; Waf1; mda6; CAP20; Cdkn1; p21WAF; p2
Name
Cyclin-dependent kinase inhibitor 1A
Organism
Mus musculus (AnAge)
Known functions and activities
Cell cycle

Potential relevance to longevity and/or ageing

Observations
Deletion of p21 prolongs the lifespan of telomerase-deficient mice with dysfunctional telomeres and improves the repopulation capacity and self-renewal of hematopoietic stem cells.
Lifespan Effect
Increase
Genetic Manipulation
Deletion
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as CDKN1A
    LongevityMap
    • A homolog of this gene for Homo sapiens is present as CDKN1A
    CellAge
    • A homolog of this gene for Homo sapiens is present as CDKN1A

    Homologs in other organisms

    Danio rerio
    cdkn1a
    Homo sapiens
    CDKN1A
    Rattus norvegicus
    Cdkn1a

    External links

    Mouse Genome Informatics
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (12575)
    Homologues
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    UniProt
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    Internet
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