Caenorhabditis elegansGenAge entry for vrk-1 (Caenorhabditis elegans)

Gene information (ID: 721)

Symbol
vrk-1
Name
Vaccinia Related Kinase
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Signalling

Potential relevance to longevity and/or ageing

Observations
RNA interference decreased median lifespan by 36% in wild type animals, 54% in a daf-2 background and 12% in daf-2/daf-16 double mutants.
% change in avg or median lifespan
Median lifespan is 36% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    vrk2
    Drosophila melanogaster
    BcDNA.LD23371
    Homo sapiens
    VRK2
    Mus musculus
    Vrk3
    Rattus norvegicus
    Vrk3

    External links

    WormBase
    Search
    Ensembl
    Search
    Entrez Gene
    View on Entrez Gene database (174004)
    Homologues
    Search HomoloGene
    UniProt
    Search
    Internet
    Search Google or Search Google Scholar