Caenorhabditis elegansGenAge entry for vps-37 (Caenorhabditis elegans)

Gene information (ID: 102)

Symbol
vps-37
Name
related to yeast Vacuolar Protein Sorting factor
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
ESCRT-I subunit

Potential relevance to longevity and/or ageing

Observations
RNA interference decreased median lifespan by 44% in wild type animals, 47% in a daf-2 background and 33% in daf-2/daf-16 double mutants.
% change in avg or median lifespan
Median lifespan is 44% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    zgc:153996
    Drosophila melanogaster
    CG1115
    Homo sapiens
    VPS37C
    Mus musculus
    Vps37c
    Rattus norvegicus
    Vps37c

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (178944)
    Homologues
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    UniProt
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    Internet
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