GenAge entry for vit-1 (Caenorhabditis elegans)
Gene information (ID: 2155)
- Caenorhabditis elegans (AnAge)
Potential relevance to longevity and/or ageing
- Vit-1 RNAi was sufficient to silence vit-1 to vit-5. Downregulation of vit gene expression increased the lifespan of worms by 16-40%. Vit silencing failed to extend the life span of nhr-49 and nhr-80 mutant worms.
- % change in avg or median lifespan
- Mean lifespan is 40% higher.
- Lifespan Effect
- Genetic Manipulation
- RNA interference
- Longevity Category
- Primary reference
Homologs in other organisms
No homologs found