Caenorhabditis elegansGenAge entry for unc-4 (Caenorhabditis elegans)

Gene information (ID: 706)

Symbol
unc-4
Name
UNCoordinated
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Encodes a neuronal homeodomain transcription factor

Potential relevance to longevity and/or ageing

Observations
Mutation results in a two-fold life-extension in males.
% change in avg or median lifespan
Lifespan is two-fold higher.
Lifespan Effect
Increase
Genetic Manipulation
Mutation
Primary reference

    Homologs in other organisms

    Danio rerio
    alx4b
    Homo sapiens
    DMBX1
    Mus musculus
    Dmbx1
    Rattus norvegicus
    Dmbx1

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (174544)
    Homologues
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    UniProt
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    Internet
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