Caenorhabditis elegansGenAge entry for unc-31 (Caenorhabditis elegans)

Gene information (ID: 704)

Symbol
unc-31
Name
UNCoordinated
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
May be involved in the insulin receptor signalling pathway

Potential relevance to longevity and/or ageing

Observations
Unc-1 worm mutants display an increased mean lifespan (by 34-36%)
% change in avg or median lifespan
Mean lifespan is approximately 35% higher.
Lifespan Effect
Increase
Genetic Manipulation
Mutation
Longevity Category
Anti-Longevity
Primary reference
    Observations
    Mutation increases hermaphrodite lifespan by approximately 70% and male lifespan by 150%.
    % change in avg or median lifespan
    Lifespan is up to 150% higher.
    Lifespan Effect
    Increase
    Genetic Manipulation
    Mutation
    Longevity Category
    Anti-Longevity
    Primary reference

      Homologs in other organisms

      Danio rerio
      cadps2
      Drosophila melanogaster
      Caps
      Homo sapiens
      CADPS2
      Mus musculus
      Cadps2
      Rattus norvegicus
      Cadps2

      External links

      WormBase
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      Ensembl
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      Entrez Gene
      View on Entrez Gene database (178233)
      Homologues
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      UniProt
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      Internet
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