Caenorhabditis elegansGenAge entry for unc-13 (Caenorhabditis elegans)

Gene information (ID: 702)

Symbol
unc-13
Name
UNCoordinated
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Encodes factor involved in synaptic transmission

Potential relevance to longevity and/or ageing

Observations
Mutation results in a 150% life-extension in males.
% change in avg or median lifespan
Lifespan is 150% higher.
Lifespan Effect
Increase
Genetic Manipulation
Mutation
Longevity Category
Anti-Longevity
Primary reference
    Observations
    RNAi led to a 16% maximum lifespan increase.
    % change in max lifespan
    Maximum lifespan is 22% higher.
    Lifespan Effect
    Increase
    Genetic Manipulation
    Mutation
    Longevity Category
    Anti-Longevity
    Primary reference

      Homologs in other organisms

      Danio rerio
      unc13ba
      Homo sapiens
      UNC13C
      Mus musculus
      Unc13c
      Rattus norvegicus
      Unc13c

      External links

      WormBase
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      Ensembl
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      Entrez Gene
      View on Entrez Gene database (172497)
      Homologues
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      UniProt
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      Internet
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