Caenorhabditis elegansGenAge entry for try-1 (Caenorhabditis elegans)

Gene information (ID: 2118)

Symbol
try-1
Name
TRYpsin-like protease
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
In a large scale screen downregulation of try-1 in worms increased mean lifespan by >5%.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    si:dkey-22n8.2
    Drosophila melanogaster
    CG9372
    Homo sapiens
    PRSS22
    Mus musculus
    Tmprss5
    Rattus norvegicus
    Prss21

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (173856)
    Homologues
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    UniProt
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    Internet
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