Caenorhabditis elegansGenAge entry for trpa-1 (Caenorhabditis elegans)

Gene information (ID: 1793)

Symbol
trpa-1
Name
Protein TRPA-1
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
Overexpression of wild-type trpa-1 extends lifespan at 20C and 15C (but not at 25C). Additionally, trpa-1 null mutant worms are short lived at 20C and 15C (but not at 25C).
% change in avg or median lifespan
Average lifespan is up to 33.5% higher.
Lifespan Effect
Increase
Genetic Manipulation
Overexpression
Longevity Category
Pro-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    trpa1a
    Drosophila melanogaster
    TrpA1
    Homo sapiens
    TRPA1
    Mus musculus
    Trpa1
    Rattus norvegicus
    Trpa1

    External links

    WormBase
    Search
    Ensembl
    Search
    Entrez Gene
    View on Entrez Gene database (178118)
    Homologues
    Search HomoloGene
    UniProt
    Search
    Internet
    Search Google or Search Google Scholar