Caenorhabditis elegansGenAge entry for tkt-1 (Caenorhabditis elegans)

Gene information (ID: 227)

Symbol
tkt-1
Name
Protein TKT-1
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Transketolase, involved in sugar-phosphate metabolism

Potential relevance to longevity and/or ageing

Observations
RNA interference increased mean lifespan by 25%.
% change in avg or median lifespan
Average lifespan is 25% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    LOC557518
    Drosophila melanogaster
    CG5103-RA
    Homo sapiens
    TKTL2
    Mus musculus
    Tktl1
    Rattus norvegicus
    Tktl1
    Saccharomyces cerevisiae
    TKL2
    Schizosaccharomyces pombe
    SPBC2G5.05

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (177906)
    Homologues
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    UniProt
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    Internet
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