Caenorhabditis elegansGenAge entry for sptf-3 (Caenorhabditis elegans)

Gene information (ID: 987)

Symbol
sptf-3
Name
Specificity Protein) Transcription Factor
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
Post-developmental RNAi of sptf-3 shortens lifespan of wild type worms.
% change in max lifespan
Maximum lifespan is 37% lower.
% change in avg or median lifespan
Average lifespan is 22.9% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Post-developmental RNA interference
Longevity Category
Pro-Longevity
Primary reference
    Observations
    24% mean decrease in lifespan
    % change in avg or median lifespan
    Average lifespan is 24% lower.
    Lifespan Effect
    Decrease
    Genetic Manipulation
    RNA interference
    Longevity Category
    Pro-Longevity
    Primary reference

      Homologs in other organisms

      Danio rerio
      sp1
      Drosophila melanogaster
      btd
      Homo sapiens
      ZNF853
      Mus musculus
      Zkscan1
      Rattus norvegicus
      Sp1
      Saccharomyces cerevisiae
      CRZ1

      External links

      WormBase
      Search
      Ensembl
      Search
      Entrez Gene
      View on Entrez Gene database (189783)
      Homologues
      Search HomoloGene
      UniProt
      Search
      Internet
      Search Google or Search Google Scholar