Caenorhabditis elegansGenAge entry for spg-7 (Caenorhabditis elegans)

Gene information (ID: 753)

Symbol
spg-7
Name
human SPG (spastic paraplegia)
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
AAA+-type ATPase peptidase

Potential relevance to longevity and/or ageing

Observations
RNA interference in adulthood resulted in a 23% increase in mean lifespan.
% change in avg or median lifespan
Average lifespan is 23% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Saccharomyces cerevisiae is present as AFG3
    GenDR gene manipulations
    • A homolog of this gene for Saccharomyces cerevisiae is present as AFG3

    Homologs in other organisms

    Danio rerio
    uncharacterized_E7F6
    Drosophila melanogaster
    CG6512
    Homo sapiens
    AFG3L2
    Mus musculus
    Afg3l1
    Rattus norvegicus
    Afg3l1
    Saccharomyces cerevisiae
    AFG3
    Schizosaccharomyces pombe
    yta12

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (171915)
    Homologues
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    UniProt
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    Internet
    Search Google or Search Google Scholar