Caenorhabditis elegansGenAge entry for sgk-1 (Caenorhabditis elegans)

Gene information (ID: 599)

Symbol
sgk-1
Name
Serum- and Glucocorticoid- inducible kinase homolog
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
SGK-1 acts in parallel to the AKT kinases to mediate DAF-2 signalling

Potential relevance to longevity and/or ageing

Observations
Deletion results in defective egg-laying, extended generation time, increased stress resistance, and life-extension.
Lifespan Effect
Increase
Genetic Manipulation
Deletion
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    sgk2a
    Homo sapiens
    SGK2
    Mus musculus
    Sgk2
    Rattus norvegicus
    Sgk2
    Schizosaccharomyces pombe
    sck1

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (181697)
    Homologues
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    UniProt
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    Internet
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