Caenorhabditis elegansGenAge entry for sgk-1 (Caenorhabditis elegans)

Gene information (ID: 599)

Symbol
sgk-1
Name
Serum- and Glucocorticoid- inducible kinase homolog
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
SGK-1 acts in parallel to the AKT kinases to mediate DAF-2 signalling

Potential relevance to longevity and/or ageing

Observations
Deletion results in defective egg-laying, extended generation time, increased stress resistance, and life-extension.
Lifespan Effect
Increase
Genetic Manipulation
Deletion
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Saccharomyces cerevisiae is present as SCH9
    • A homolog of this gene for Saccharomyces cerevisiae is present as YPK1
    GenAge microarray genes
    • A homolog of this gene for Homo sapiens is present as SGK1
    GenDR gene manipulations
    • A homolog of this gene for Saccharomyces cerevisiae is present as SCH9
    LongevityMap
    • A homolog of this gene for Homo sapiens is present as SGK1
    • A homolog of this gene for Homo sapiens is present as SGK3
    CellAge
    • A homolog of this gene for Homo sapiens is present as SGK1

    Homologs in other organisms

    Danio rerio
    sgk2a
    Danio rerio
    sgk1
    Danio rerio
    sgk2b
    Danio rerio
    sgk3
    Danio rerio
    si:ch211-195b13.1
    Homo sapiens
    SGK2
    Homo sapiens
    SGK1
    Homo sapiens
    C8orf44-SGK3
    Homo sapiens
    SGK3
    Mus musculus
    Sgk3
    Mus musculus
    Sgk1
    Mus musculus
    Sgk2
    Rattus norvegicus
    Sgk3
    Rattus norvegicus
    Sgk2
    Rattus norvegicus
    Sgk1
    Saccharomyces cerevisiae
    SCH9
    Saccharomyces cerevisiae
    YPK1
    Saccharomyces cerevisiae
    YPK2
    Schizosaccharomyces pombe
    sck1

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (181697)
    Homologues
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    UniProt
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    Internet
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