Caenorhabditis elegansGenAge entry for set-2 (Caenorhabditis elegans)

Gene information (ID: 977)

Symbol
set-2
Name
SET (trithorax/polycomb) domain containing
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
20% mean lifespan extension
% change in avg or median lifespan
Average lifespan is 20% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference
    Observations
    Set-2 deficiency in the parental generation extend the lifespan of descendants up until the third generation.
    % change in avg or median lifespan
    Lifespan is up to 30% higher.
    Lifespan Effect
    Increase
    Genetic Manipulation
    Mutation
    Longevity Category
    Anti-Longevity
    Primary reference

      Homologs in other organisms

      Danio rerio
      setd1a
      Drosophila melanogaster
      Set1
      Homo sapiens
      SETD1A
      Mus musculus
      Setd1a
      Rattus norvegicus
      Setd1b

      External links

      WormBase
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      Ensembl
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      Entrez Gene
      View on Entrez Gene database (175662)
      Homologues
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      UniProt
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      Internet
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