Caenorhabditis elegansGenAge entry for rpb-8 (Caenorhabditis elegans)

Gene information (ID: 1775)

Symbol
rpb-8
Name
Protein RPB-8
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
Post-developmental RNAi of rpb-8 extends lifespan of wild type worms.
% change in max lifespan
Maximum lifespan is not significantly changed.
% change in avg or median lifespan
Average lifespan is 6.4% higher.
Lifespan Effect
Increase
Genetic Manipulation
Post-developmental RNA interference
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    zgc:110289
    Drosophila melanogaster
    Rpb8
    Homo sapiens
    POLR2H
    Mus musculus
    Polr2h
    Rattus norvegicus
    LOC100912534
    Saccharomyces cerevisiae
    RPB8
    Schizosaccharomyces pombe
    rpb8

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (175660)
    Homologues
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    UniProt
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    Internet
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