Drosophila melanogasterGenAge entry for rb (Drosophila melanogaster)

Gene information (ID: 541)

Symbol
rb
Aliases
AP-3beta; beta3; cg11427; CG11427; Dmel\CG11427; Rb
Name
ruby
Organism
Drosophila melanogaster (AnAge)
Known functions and activities
B-subunit of AP-3 complex

Potential relevance to longevity and/or ageing

Observations
Loss-of-function mutation reduces maximum lifespan by 23%.
% change in max lifespan
Maximum lifespan is 23% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Mutation
Longevity Category
Pro-Longevity
Primary reference

    Homologs in other organisms

    Caenorhabditis elegans
    apb-3
    Danio rerio
    ap3b2
    Homo sapiens
    AP3B1
    Mus musculus
    Ap3b1
    Rattus norvegicus
    Ap3b2
    Saccharomyces cerevisiae
    APL6
    Schizosaccharomyces pombe
    apl6

    External links

    FlyBase
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    Entrez Gene
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    Homologues
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    UniProt
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    Internet
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