Drosophila melanogasterGenAge entry for ppk28 (Drosophila melanogaster)

Gene information (ID: 1925)

Symbol
ppk28
Name
pickpocket 28
Organism
Drosophila melanogaster (AnAge)

Potential relevance to longevity and/or ageing

Observations
Female ppk28-null mutant flies display an increase in mean (up to 44%) and maximum lifespan in two different genetic backgrounds (w and yw). Loss of ppk28 also extended male lifespan in both genetic backgrounds, although to a lesser degree.
% change in max lifespan
Maximum lifespan is up to 25% higher.
% change in avg or median lifespan
Mean lifespan is 25-44% higher.
Lifespan Effect
Increase
Genetic Manipulation
Mutation
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    Caenorhabditis elegans
    unc-105
    Homo sapiens
    ASIC5
    Mus musculus
    Scnn1a
    Rattus norvegicus
    Scnn1a

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (32671)
    Homologues
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    UniProt
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    Internet
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