Caenorhabditis elegansGenAge entry for pnk-1 (Caenorhabditis elegans)

Gene information (ID: 510)

Symbol
pnk-1
Name
PaNtothenate Kinase
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Pantothenate kinase PanK involved in coenzyme A biosynthesis

Potential relevance to longevity and/or ageing

Observations
RNA interference shortened lifespan.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference
    Observations
    RNAi let to a 42% decrease in median lifespan in daf-2 background and a 18% decrease in lifespan in daf-2/daf-16 double mutant background.
    Lifespan Effect
    Decrease
    Genetic Manipulation
    RNA interference
    Longevity Category
    Pro-Longevity
    Primary reference

      Homologs in other organisms

      Danio rerio
      pank2
      Drosophila melanogaster
      fbl
      Homo sapiens
      PANK3
      Mus musculus
      Pank3
      Rattus norvegicus
      Pank1
      Saccharomyces cerevisiae
      CAB1
      Schizosaccharomyces pombe
      SPBC4B4.01c

      External links

      WormBase
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      Ensembl
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      Entrez Gene
      View on Entrez Gene database (172327)
      Homologues
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      UniProt
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      Internet
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