Caenorhabditis elegansGenAge entry for pkg-1 (Caenorhabditis elegans)

Gene information (ID: 213)

Symbol
pkg-1
Name
EGg Laying defective
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Cyclic GMP-dependant protein kinase involved in multiple signalling pathway

Potential relevance to longevity and/or ageing

Observations
Mutations extend lifespan by up to 55%.
% change in avg or median lifespan
Lifespan is up to 55% higher.
Lifespan Effect
Increase
Genetic Manipulation
Mutation
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    prkg1a
    Drosophila melanogaster
    Pkg21D
    Homo sapiens
    PRKG1
    Mus musculus
    Prkg1
    Rattus norvegicus
    Prkg2

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (176991)
    Homologues
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    UniProt
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    Internet
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