Caenorhabditis elegansGenAge entry for pdk-1 (Caenorhabditis elegans)

Gene information (ID: 499)

Symbol
pdk-1
Name
PDK-class protein kinase
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Serine/threonine kinase

Potential relevance to longevity and/or ageing

Observations
Loss-of-function alleles extend lifespan by 60%.
% change in avg or median lifespan
Lifespan is 60% higher.
Lifespan Effect
Increase
Genetic Manipulation
Mutation
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    pdpk1b
    Drosophila melanogaster
    Pdk1
    Homo sapiens
    PDPK2
    Mus musculus
    Pdpk1
    Rattus norvegicus
    Pdpk1
    Schizosaccharomyces pombe
    ppk21

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (180475)
    Homologues
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    UniProt
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    Internet
    Search Google or Search Google Scholar