Caenorhabditis elegansGenAge entry for pat-4 (Caenorhabditis elegans)

Gene information (ID: 494)

Symbol
pat-4
Name
Paralysed Arrest at Two-fold
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Integrin-mediated muscle cell attachments during embryogenesis

Potential relevance to longevity and/or ageing

Observations
RNA interference increased mean lifespan by 9-16%.
% change in avg or median lifespan
Average lifespan is 9-16% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference
    Observations
    Post developmental RNAi let to a 13% mean lifespan extension.
    % change in avg or median lifespan
    Average lifespan is 13% higher.
    Lifespan Effect
    Increase
    Genetic Manipulation
    RNA interference
    Longevity Category
    Anti-Longevity
    Primary reference
      Observations
      RNAi let to a 24% mean lifespan extension.
      % change in avg or median lifespan
      Average lifespan is 24% higher.
      Lifespan Effect
      Increase
      Genetic Manipulation
      RNA interference
      Longevity Category
      Anti-Longevity
      Primary reference

        In other databases

        GenAge model organism genes
        • A homolog of this gene for Drosophila melanogaster is present as Ilk

        Homologs in other organisms

        Danio rerio
        ilk
        Drosophila melanogaster
        Ilk
        Homo sapiens
        ILK
        Mus musculus
        Ilk
        Rattus norvegicus
        Ilk

        External links

        WormBase
        Search
        Ensembl
        Search
        Entrez Gene
        View on Entrez Gene database (175175)
        Homologues
        Search HomoloGene
        UniProt
        Search
        Internet
        Search Google or Search Google Scholar