Caenorhabditis elegansGenAge entry for pat-10 (Caenorhabditis elegans)

Gene information (ID: 1957)

Symbol
pat-10
Name
Paralysed Arrest at Two-fold
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
Loss of pat-10 expression results in a reduction in thermotolerance and longevity (median ~35% lower). Contrastly, worms overexpressing pat-10 display significantly increased thermotolerance and extended lifespan (median ~30% higher).
% change in avg or median lifespan
Median lifespan is approximately 30% higher.
Lifespan Effect
Increase
Genetic Manipulation
Overexpression
Longevity Category
Pro-Longevity
Primary reference

    Homologs in other organisms

    No homologs found

    External links

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    Entrez Gene
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    Internet
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