Caenorhabditis elegansGenAge entry for pak-1 (Caenorhabditis elegans)

Gene information (ID: 1897)

Symbol
pak-1
Name
Serine/threonine-protein kinase pak-1
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
PAK1-deficient worms (RB689) exhibit an increased lifespan when compared to N2 controls.
% change in avg or median lifespan
Median lifespan is 50% higher.
Lifespan Effect
Increase
Genetic Manipulation
Mutation
Primary reference

    Homologs in other organisms

    Danio rerio
    CR352290.1
    Drosophila melanogaster
    Pak
    Homo sapiens
    PAK2
    Mus musculus
    Pak2
    Rattus norvegicus
    Pak2
    Saccharomyces cerevisiae
    STE20
    Schizosaccharomyces pombe
    shk1

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (180873)
    Homologues
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    UniProt
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    Internet
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