Caenorhabditis elegansGenAge entry for pab-1 (Caenorhabditis elegans)

Gene information (ID: 490)

Symbol
pab-1
Name
PolyA Binding protein
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
PolyA Binding protein

Potential relevance to longevity and/or ageing

Observations
RNA interference of pab-1 results in an increased lifespan.
% change in avg or median lifespan
Mean lifespan is 24% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference
    Observations
    RNA interference in adulthood resulted in a 30% mean lifespan extension.
    % change in avg or median lifespan
    Average lifespan is 30% higher.
    Lifespan Effect
    Increase
    Genetic Manipulation
    RNA interference
    Longevity Category
    Anti-Longevity
    Primary reference

      Homologs in other organisms

      Homo sapiens
      PABPC1L
      Schizosaccharomyces pombe
      pab1

      External links

      WormBase
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      Ensembl
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      Entrez Gene
      View on Entrez Gene database (172920)
      Homologues
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      UniProt
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      Internet
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