Caenorhabditis elegansGenAge entry for old-1 (Caenorhabditis elegans)

Gene information (ID: 673)

Symbol
old-1
Name
Overexpression Longevity Determinant
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Tyrosine kinase receptor

Potential relevance to longevity and/or ageing

Observations
Overexpression in transgenic animals increased lifespan by about 65% and increases stress resistance without altering development or fertility.
% change in avg or median lifespan
Lifespan is about 65% higher.
Lifespan Effect
Increase
Genetic Manipulation
Overexpression
Longevity Category
Pro-Longevity
Primary reference

    Homologs in other organisms

    No homologs found

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (191737)
    Homologues
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    UniProt
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    Internet
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