Caenorhabditis elegansGenAge entry for odr-3 (Caenorhabditis elegans)

Gene information (ID: 481)

Symbol
odr-3
Name
ODoRant response abnormal
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
G Protein, Alpha subunit

Potential relevance to longevity and/or ageing

Observations
Worms with a odr-3 loss-of-function mutation display an increased lifespan in a temperature-independent manner.
% change in avg or median lifespan
Mean lifespan is up to 27% higher.
Lifespan Effect
Increase
Genetic Manipulation
Mutation
Longevity Category
Anti-Longevity
Primary reference
    Observations
    Loss-of-function mutation extended mean lifespan by 10-30% but not maximum lifespan. Life-extension was dependent on daf-16 but cumulative with daf-2 mutations.
    % change in avg or median lifespan
    Average lifespan is 10-30% higher.
    Lifespan Effect
    Increase
    Genetic Manipulation
    Mutation
    Longevity Category
    Anti-Longevity
    Primary reference

      Homologs in other organisms

      Saccharomyces cerevisiae
      GPA1

      External links

      WormBase
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      Entrez Gene
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      Homologues
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      UniProt
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      Internet
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