Caenorhabditis elegansGenAge entry for nuo-4 (Caenorhabditis elegans)

Gene information (ID: 479)

Symbol
nuo-4
Name
NADH Ubiquinone Oxidoreductase
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
NADH:ubiquinone oxidoreductase, NDUFA10/42kDa subunit

Potential relevance to longevity and/or ageing

Observations
RNA interference extends lifespan.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference
    Observations
    RNAi let to a 38% mean lifespan extension.
    % change in avg or median lifespan
    Average lifespan is 38% higher.
    Lifespan Effect
    Increase
    Genetic Manipulation
    RNA interference
    Longevity Category
    Anti-Longevity
    Primary reference

      Homologs in other organisms

      Danio rerio
      ndufa10
      Drosophila melanogaster
      ND42
      Homo sapiens
      NDUFA10
      Mus musculus
      Ndufa10
      Rattus norvegicus
      Ndufa10

      External links

      WormBase
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      Ensembl
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      Entrez Gene
      View on Entrez Gene database (176001)
      Homologues
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      UniProt
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      Internet
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