Caenorhabditis elegansGenAge entry for nuo-3 (Caenorhabditis elegans)

Gene information (ID: 478)

Symbol
nuo-3
Name
NADH Ubiquinone Oxidoreductase
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
NADH:ubiquinone oxidoreductase, NDUFA6/B14 subunit

Potential relevance to longevity and/or ageing

Observations
RNA interference extends lifespan.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference
    Observations
    RNAi let to a 77% mean lifespan extension.
    % change in avg or median lifespan
    Average lifespan is 77% higher.
    Lifespan Effect
    Increase
    Genetic Manipulation
    RNA interference
    Longevity Category
    Anti-Longevity
    Primary reference
      Observations
      RNAi let to a 40% mean lifespan extension.
      % change in avg or median lifespan
      Average lifespan is 40% higher.
      Lifespan Effect
      Increase
      Genetic Manipulation
      RNA interference
      Longevity Category
      Anti-Longevity
      Primary reference

        Homologs in other organisms

        Danio rerio
        ndufa6
        Drosophila melanogaster
        CG7712
        Homo sapiens
        NDUFA6
        Mus musculus
        Ndufa6
        Rattus norvegicus
        Ndufa6

        External links

        WormBase
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        Ensembl
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        Entrez Gene
        View on Entrez Gene database (178404)
        Homologues
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        UniProt
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        Internet
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