Caenorhabditis elegansGenAge entry for nuo-1 (Caenorhabditis elegans)

Gene information (ID: 476)

Symbol
nuo-1
Name
NADH Ubiquinone Oxidoreductase
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
Mutations result in developmental arrest and increased lifespan.
Lifespan Effect
Increase
Genetic Manipulation
Mutation
Longevity Category
Anti-Longevity
Primary reference
    Observations
    Post developmental RNAi let to a 23% mean lifespan extension.
    % change in avg or median lifespan
    Average lifespan is 23% higher.
    Lifespan Effect
    Increase
    Genetic Manipulation
    RNA interference
    Longevity Category
    Anti-Longevity
    Primary reference
      Observations
      RNAi let to a 50% mean lifespan extension.
      % change in avg or median lifespan
      Average lifespan is 50% higher.
      Lifespan Effect
      Increase
      Genetic Manipulation
      RNA interference
      Longevity Category
      Anti-Longevity
      Primary reference

        In other databases

        LongevityMap
        • A homolog of this gene for Homo sapiens is present as NDUFV1

        Homologs in other organisms

        Danio rerio
        ndufv1
        Drosophila melanogaster
        CG9140
        Homo sapiens
        NDUFV1
        Mus musculus
        Ndufv1
        Rattus norvegicus
        Ndufv1
        Schizosaccharomyces pombe
        SPBC18E5.10

        External links

        WormBase
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        Ensembl
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        Entrez Gene
        View on Entrez Gene database (174696)
        Homologues
        Search HomoloGene
        UniProt
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        Internet
        Search Google or Search Google Scholar