Caenorhabditis elegansGenAge entry for ntl-3 (Caenorhabditis elegans)

Gene information (ID: 474)

Symbol
ntl-3
Name
NOT-Like (yeast CCR4/NOT complex component)
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
NOT3/NOT5 protein

Potential relevance to longevity and/or ageing

Observations
RNA interference decreased median lifespan by 40% in a daf-2 background and 11% in daf-2/daf-16 double mutants.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    cnot3b
    Homo sapiens
    CNOT3
    Mus musculus
    Cnot3
    Rattus norvegicus
    Cnot3
    Saccharomyces cerevisiae
    NOT3
    Schizosaccharomyces pombe
    not3

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (176614)
    Homologues
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    UniProt
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    Internet
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