Caenorhabditis elegansGenAge entry for npp-3 (Caenorhabditis elegans)

Gene information (ID: 469)

Symbol
npp-3
Name
Nuclear Pore complex Protein
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Nucleoporin

Potential relevance to longevity and/or ageing

Observations
RNA interference decreased median lifespan by 14% in wild type animals, 36% in a daf-2 background and 11% in daf-2/daf-16 double mutants.
% change in avg or median lifespan
Median lifespan is 14% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    nup205
    Homo sapiens
    NUP205
    Mus musculus
    Nup205
    Rattus norvegicus
    Nup205

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (174823)
    Homologues
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    UniProt
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    Internet
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