Caenorhabditis elegansGenAge entry for npp-2 (Caenorhabditis elegans)

Gene information (ID: 468)

Symbol
npp-2
Name
Nuclear Pore complex Protein
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Nuclear pore complex component

Potential relevance to longevity and/or ageing

Observations
RNA interference decreased median lifespan by 11% in wild type animals, 38% in a daf-2 background and 22% in daf-2/daf-16 double mutants.
% change in avg or median lifespan
Average lifespan is 11% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    nup85
    Drosophila melanogaster
    Nup75
    Homo sapiens
    NUP85
    Mus musculus
    Nup85
    Rattus norvegicus
    Nup85

    External links

    WormBase
    Search
    Ensembl
    Search
    Entrez Gene
    View on Entrez Gene database (172611)
    Homologues
    Search HomoloGene
    UniProt
    Search
    Internet
    Search Google or Search Google Scholar