Caenorhabditis elegansGenAge entry for nac-2 (Caenorhabditis elegans)

Gene information (ID: 452)

Symbol
nac-2
Name
NADC (Na+-coupled dicarboxylate transporter) family
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Na -coupled dicarboxylate transporter

Potential relevance to longevity and/or ageing

Observations
RNA interference knockdown leads to an increase in average (19%) and maximal lifespan (50%).
% change in max lifespan
Maximum lifespan is 50% higher.
% change in avg or median lifespan
Average lifespan is 19% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    Schizosaccharomyces pombe
    SPBC3B8.04c

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (187898)
    Homologues
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    UniProt
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    Internet
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