Drosophila melanogasterGenAge entry for myo (Drosophila melanogaster)

Gene information (ID: 1880)

Symbol
myo
Name
myoglianin
Organism
Drosophila melanogaster (AnAge)

Potential relevance to longevity and/or ageing

Observations
Similarly to Mnt, Myoglianin (myo) overexpression in flies lowers climbing defects and increases both median and maximum lifespan. Contrastly, RNAi against myoglianin shortens median lifespan and results in more age-related climbing defects.
% change in max lifespan
Maximum lifespan is aproximately 20% higher.
% change in avg or median lifespan
Median lifespan is aproximately 25% higher.
Lifespan Effect
Increase
Genetic Manipulation
Overexpression
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Mus musculus is present as Mstn
    LongevityMap
    • A homolog of this gene for Homo sapiens is present as MSTN

    Homologs in other organisms

    Danio rerio
    mstna
    Homo sapiens
    MSTN
    Mus musculus
    Mstn
    Rattus norvegicus
    Gdf11

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (43811)
    Homologues
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    UniProt
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    Internet
    Search Google or Search Google Scholar