Caenorhabditis elegansGenAge entry for mnk-1 (Caenorhabditis elegans)

Gene information (ID: 438)

Symbol
mnk-1
Name
MAP kinase iNtegrating Kinase (MNK) homolog
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Regulation of signalling

Potential relevance to longevity and/or ageing

Observations
RNA interference shortened wild-type (20%) and ife-2 mutant (15%) maximum lifespan.
% change in max lifespan
Maximum lifespan is 20% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference

    Homologs in other organisms

    Homo sapiens
    MKNK2
    Mus musculus
    Mknk2
    Rattus norvegicus
    Mknk2

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (174623)
    Homologues
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    UniProt
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    Internet
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