Drosophila melanogasterGenAge entry for mle (Drosophila melanogaster)

Gene information (ID: 868)

Symbol
mle
Aliases
CG11680; Dmel\CG11680; mak; MLE; mll; mls; nap; nap[ts]
Name
Maleless
Organism
Drosophila melanogaster (AnAge)

Potential relevance to longevity and/or ageing

Observations
Homozygous mutant flies (mle napts) display a shortened median lifespan and increased frailty in both males and females.
% change in avg or median lifespan
Median male lifespan is 47.5% lower; Median female lifespan is 39% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Mutations
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    CellAge
    • A homolog of this gene for Homo sapiens is present as DHX9

    Homologs in other organisms

    Caenorhabditis elegans
    rha-1
    Danio rerio
    dhx9
    Homo sapiens
    DHX9
    Mus musculus
    Dhx9
    Rattus norvegicus
    Dhx9

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (35523)
    Homologues
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    UniProt
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    Internet
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